Molecular modeling revealed that ligand dissociation from ...

2013-7-1 · Here, classical molecular dynamics (MD) and random acceleration molecular dynamics (RAMD) simulations were combined to investigate the effects of TR heterodimerization on T3 dissociation from a TRα-RXR LBD heterodimer and from the LBDs of TRα and TRβ.RAMD is an enhanced sampling method that applies a small randomly oriented force to the center of mass of ligands to accelerate ligand ...

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2018-9-30 · 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44 ...

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Combined application of biochar and nitrogen fertilizer ...

2020-4-13 · Introduction. Rice noodles are a staple and traditional food in China and other Southeast Asian countries (Xuan et al., 2019) ina''s rice cultivation area accounts for 20% of the global rice production area and covers 30 M ha, comprising 23% of all croplands in the country (Qian et al., 2014).The average amount of nitrogen (N) fertilizer applied to paddy rice …

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Developmental origin and -specific risk for infections ...

2018-10-8 · The intrauterine environment is an important determinant of immunity later in life of the offspring. An altered prenatal immune development can result in a high postnatal risk for infections, chronic immune diseases, and autoimmunity. Many of these immune diseases show a strong bias, such as a high incidence of autoimmune diseases and allergies in adult females or a high risk for ...

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Anticholinergika | SpringerLink

Steinbrecher W (1973) Über eine Methode der Objektivierung von Tremorerscheinungen und deren therapeutischer Beeinflußbarkeit. Med Welt 24: 237–240 PubMed Google Scholar Strang RR (1986) Kemadrin in the treatment of parkinsonism: a double blind and one-year follow-up study.

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An Interventionalist''s Guide to Hemoptysis in Cystic ...

2018-3-12 · Abstract. Massive hemoptysis occurs in a minority of patients with cystic fibrosis, with an annual incidence of 1%. Although rare, massive hemoptysis can be a severe and potentially fatal complication of this disease. Beyond the acute life-threatening event, hemoptysis in patients with cystic fibrosis has been associated with faster decline in ...

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An Interventionalist''s Guide to Hemoptysis in Cystic ...

2018-3-12 · Abstract. This article serves as a practical guide for interventional radiologists to confidently evaluate and treat hemoptysis in patients with cystic fibrosis; it includes a review of the complexities of bronchial artery circulation as well as historical and modern perspectives on embolotherapy. Massive hemoptysis occurs in …

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Frontiers | Functional Role of G9a Histone ...

2015-9-25 · Post-translational modifications of DNA and histones are epigenetic mechanisms, which affect the chromatin structure, ultimately leading to gene expression changes. A number of different epigenetic enzymes are actively involved in the addition or the removal of various …

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Frontiers | Functional Role of G9a Histone ...

Genomics'' most flexible and powerful tool to accelerate your research! Next Generation Sequencing (NGS) has become a key analysis method for biological research, enabling researchers to obtain a global view of biological processes. Advice and guidance for sequencing projects are offered by our team, which relies on more than 10 years of experience with sequencing systems, high-throughput ...

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Mechanisms in protein O-glycan biosynthesis and clinical ...

2006-4-1 · Structures of O-Linked Glycans The O-glycosylation process produces an immense multiplicity of chemical structures. Each monosaccharide has 3 or 4 attachment sites for linkage of other sugar residues and can form a glycosidic linkage in an [alpha] or [beta] configuration, allowing glycan structures to form branches.

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Stimulation of Interleukin-6 and Prostaglandin E2 ...

1993-11-1 · INTERLEUKIN-6 (IL-6) is a multifunctional cytokine that regulates immune function and the acute-phase response to inflammatory stimuli.1, 2 Normally, when an individual is exposed to an infectious agent, serum IL-6 levels become transiently elevated and then return to nearly unde-tectible levels within a few days. Prolonged elevation of IL-6 is a marker for active disease.3, 4 Chronic high ...

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Mechanisms in Protein O-Glycan Biosynthesis and Clinical ...

The human proteome, originating from expression of the protein-coding genes of the genome, comprises ∼30 000 proteins (), a surprisingly low number considering that the genome of the nematode Caenorhabditis elegans comprises 20 000 genes ().However, a higher order of complexity of protein products in humans arises from pretranslational events, such as alternative splicing, and ...

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Multi–Detector Row CT of Hemoptysis | RadioGraphics

2006-1-1 · 41 Hsiao EI, Kirsch CM, Kagawa FT, Wehner JH, Jensen WA, Baxter RB. Utility of fiberoptic bronchoscopy before bronchial artery embolization for massive hemoptysis. AJR Am J Roentgenol 2001; 177: 861–867. Crossref, Medline, Google Scholar

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Next Generation Sequencing Facility | VBCF

Genomics'' most flexible and powerful tool to accelerate your research! Next Generation Sequencing (NGS) has become a key analysis method for biological research, enabling researchers to obtain a global view of biological processes. Advice and guidance for sequencing projects are offered by our team, which relies on more than 10 years of experience with sequencing systems, high-throughput ...

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Polytechnisches Journal

Blake ''s Steinbrecher zur Erzeugung sehr fein gebrochenen Gutes. Mit Abbildungen. Seit länger als 25 Jahren hat sich der Blake'' sche Steinbrecher als ein für die mannigfaltigste Verwendung sehr brauchbares Werkzeug bewährt. War diese Maschine auch ursprünglich nur bestimmt, Schotter für Straſsen u. dgl. zu liefern, so wurde dieselbe sehr bald als die in vielen Fällen dienlichste ...

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Heterogeneity of atherosclerotic plaque macrophage origin ...

2017-12-5 · Goossens is supported by an EU Horizon2020-MSCA-IF grant (nr 661099). M.M.P.C. Donners is funded by the Netherlands Heart Foundation (Dr. E. Dekker grant nr 2012T079 ). …

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Rozdrabniarki / kruszarki stacjonarne używane i nowe na ...

Rozdrabniarka / kruszarka stacjonarna. Niemcy, Bayern (BY) 1 076 671 zł. Kleemann MR130 ZS EVO2 Brechanlage Nr.: 178. 10.

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Anesthetic considerations in the management of Wilms ...

2021-8-28 · Wilms tumor is the most common abdominal tumor, with an incidence of 1 in 100,000 children younger than 15 years of age, and the most common solid renal tumor beyond the first year of life.

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